Cannabinoides y su nanoencapsulamiento para mejorar sus propiedades terapéuticas en padecimientos intestinales

Autores/as

  • Kevin Antonio Cárdenas Noriega Facultad de Medicina Veterinaria y Zootecnia, Universidad Autónoma de Nuevo León
  • Adolfo Soto Domínguez Facultad de Medicina Veterinaria y Zootecnia, Universidad Autónoma de Nuevo León
  • Luis Edgar Rodríguez Tovar Facultad de Medicina Veterinaria y Zootecnia, Universidad Autónoma de Nuevo León
  • Gloria Arely Guillen Melendez Facultad de Medicina, Universidad Autónoma de Nuevo León
  • Gustavo Hernandez Vidal Facultad de Medicina Veterinaria y Zootecnia, Universidad Autónoma de Nuevo León https://orcid.org/0000-0002-6229-5655
  • Uziel Castillo Velázquez Facultad de Medicina Veterinaria y Zootecnia, Universidad Autónoma de Nuevo León https://orcid.org/0000-0002-0342-1703

DOI:

https://doi.org/10.29105/agricolis.v1i2.12

Palabras clave:

cannabis, fitocannabinoides, endocannabinoidoma, Sistema endocannabinoide, nanotecnología, nanopartículas

Resumen

La planta de cannabis ha generado interés y controversia por sus diversos usos entre los que se destacan los usos medicinales. Cultivada por miles de años y distribuida globalmente, esta planta produce diversas sustancias de interés medicinal, como los fitocannabinoides, que interactúan con el sistema endocannabinoide (SEC) y la endocannabinoidoma (eCBoma) en animales. Estos sistemas están activos tanto en individuos sanos como en diversas patologías, juegan roles cruciales en la homeostasis intestinal y condicionan procesos inflamatorios. Los cannabinoides terapéuticos, conocidos por sus propiedades antiinflamatorias, enfrentan diversas limitaciones como baja solubilidad y biodisponibilidad por algunas vías de administración, además de ser vulnerables a factores ambientales y fisiológicos. La nanotecnología emerge como una solución prometedora para superar estos obstáculos en la medicina herbal. Diversas metodologías han sido desarrolladas para crear sistemas de nanoentrega, como nanopartículas poliméricas, mejorando las propiedades fisicoquímicas y el potencial terapéutico de los cannabinoides. Los avances en el nanoencapsulamiento han mostrado resultados positivos, potenciando la efectividad de los fitocannabinoides en aplicaciones médicas.

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Publicado

2024-05-31

Cómo citar

Cárdenas Noriega, K. A. (2024) «Cannabinoides y su nanoencapsulamiento para mejorar sus propiedades terapéuticas en padecimientos intestinales», Scientia Agricolis Vita, 1(2), pp. 55–67. doi: 10.29105/agricolis.v1i2.12.

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