Evaluation of the antimicrobial activity of Olea europaea (Ol-ive) against cariogenic bacterium Streptococcus mutans
DOI:
https://doi.org/10.29105/agricolis.v2i1.27Keywords:
antimicrobial agents, plant extracts, natural products, cariesAbstract
Use of plants as medicinal sources has significantly increased over the past three decades due to advantages such as safety, efficacy, and global availability. Dental caries is the most prevalent chronic bacterial disease worldwide. This study evaluated the in vitro antimicrobial potential of the aqueous extract of Olea europaea against Streptococcus mutans, the main etiological agent of dental caries. Antimicrobial activity was assessed using the disk diffusion method, and microbial susceptibility was determined through the minimum inhibitory concentration (MIC) method. The mean zone of inhibition was 7.5 ± 1.74mm at a concentration of 250 μg/mL. At all tested concentrations, S. mutans was significantly (p < 0.05) sensitive to O. europaea EA. Growth inhibition reached 67.4 ± 4.6% at 250 μg/mL, with a CI₅₀ value of 96.97 μg/mL. These findings suggest that the aqueous extract of O. europaea demonstrates promising antimicrobial activity against S. mutans, highlighting its potential in oral healthcare.
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Copyright (c) 2025 Marcela A. Gloria-Garza , Ramiro Quintanilla-Licea ; Guadalupe Gutiérrez-Soto; Aldo F. Bazaldúa-Rodríguez , Carlos J. Castillo-Zacarías, Joel H. Elizondo-Luevano
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